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Metformin and Insulin Resistance

Nov 30

What is Insulin?

Insulin is an important hormone in the human body. It is made in the pancreas where it keeps reminding the liver, our muscles and the fat cells to use the glucose that comes from the blood. This is an important step that takes place inside us as it tells the body cells to turn all the food into usable energy.

What is Insulin Resistance?

 Insulin resistance takes place when the liver, muscle and fat cells stop responding to the instructions by the insulin hormone in the human body. As an immediate effect of this, the body starts taking in less sugar than it used to from the blood cells. In return, blood sugar levels are increased, leading to diabetes and other such health conditions.

What causes insulin resistance?

 One of the key factors of having insulin resistance in the body is due to high consumption of sugar. Yes, you read that correctly. When you start consuming a high amount of sugar for too long, chances are that you might be sending constant reminders to your body cells. This will in return make your body less insulin sensitive or insulin resistant. Insulin resistance messes up the entire system of the human body. It can cause diabetes and also speed up the aging process. If you do not want to age too soon, you must maintain your blood sugar levels.

How can Metformin help?

 Metformin works as a savior when it comes to maintaining blood sugar levels in the human body. It helps in reducing the amount of sugar the liver, muscle and fat cells release into your blood. This directly signals the blood cells to respond in the normal way they were used to before your body became insulin resistant. Metformin is used as a prescribed medication for people suffering from type 2 diabetes and Polycystic Ovary Syndrome (PCOS).

Studies that suggest the use of Metformin

 Metformin has been used as a prescribed drug to deal with chronic illnesses since the 1950s. According to Healthline, Insulin resistance and insulin sensitivity are two different sides of the same coin. Being insulin resistant means that you have a low sensitivity rate to insulin and vice versa.

Here are a few studies that suggest the use of Metformin if you are insulin resistant:

According to a study done on the subject in 2012, the effects of regular exercising along with the use of Metformin for insulin sensitivity revealed that the key regulatory enzymes AMPK worked more effectively in the bodies of these people for 12 weeks. This would have not been the case had regular exercising and Metformin not been used together on people with type 2 diabetes.

A scientific review in 2003, suggested that Metformin could be used to mediate improvements in insulin sensitivity.

As per the therapeutic profile of metformin, it can be used to control blood sugar levels in diabetic patients.

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